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Syed Lokman

Molecular Biologist & Bioinformatician

Bangladesh (GMT+6)
EnglishBanglaPythonRBash

Decoding the language of cells through multi-omics, biophysics, and machine learning.

Background & Vision

I am a molecular biologist-turned-bioinformatician passionate about exploring the intersection of life sciences, computer science, and data. My research focuses on leveraging multi-omics analysis, computational biophysics, and structural biology to uncover complex cellular mechanisms and expedite rational drug discovery.

Driven by curiosity and a desire to build reproducible research tools, I transition daily between wet-lab biochemical validation and high-performance computing clusters. I believe that the future of medicine lies in our ability to translate massive sequencing and structural datasets into actionable biological insights.

Laboratory Roots

Starting at the physical bench allows me to appreciate the biochemical complexities and sample realities behind the massive computational biological datasets I process today.

WET LAB SENSE100% VALIDATED

The Bridge Between Wet Lab & Dry Lab

My scientific journey began at the lab bench. I spent hours pipetting, culturing cells, and performing PCRs. While I loved the precision of molecular biology, I soon realized that the sheer volume of biological data being generated was outpacing our ability to analyze it with traditional methods. I found myself drawn to the computational side of science.

To bridge this gap, I taught myself programming, data analysis, and advanced bioinformatics. This transition wasn't just about learning to code; it was about shifting my mindset from studying single genes to analyzing entire systems. Today, I leverage my deep understanding of wet-lab realities to design realistic, biologically relevant in silico models and pipeline architectures.

Core Research Areas

Multi-Omics Integration

Synthesizing genomic, transcriptomic, and proteomic datasets to build a holistic, system-level understanding of disease pathways and regulatory networks.

Computational Biophysics

Running molecular dynamics (MD) simulations to explore protein-ligand interactions, conformational transitions, and the physical forces driving biological assemblies.

Structural Bioinformatics

Predicting and analyzing 3D macromolecular structures using AlphaFold, molecular docking, and structural comparison tools to drive rational drug design.

Reproducible Pipelines

Developing scalable, containerized analysis workflows using Nextflow and Snakemake to ensure scientific reproducibility and ease of deployment.

Professional Timeline

2024 — Present

Lead Bioinformatician & Research Associate

Bioinformatics Research Lab

Leading a small team of researchers analyzing high-throughput single-cell RNA sequencing datasets and designing machine learning classifiers for oncology biomarkers.

2021 — 2024

Computational Biologist

Molecular Medicine Institute

Conducted high-performance virtual screening and nanosecond-scale molecular dynamics simulations to identify novel small-molecule inhibitors for therapeutic targets.

2018 — 2021

Molecular Biologist (Wet Lab)

Genomics & Therapeutics Lab

Executed cell-based assays, CRISPR gene-editing experiments, and western blotting to validate computer-generated drug candidates.

Scientific Philosophies

  • 01.Open Science: Publicly sharing datasets, source code, and methodologies to foster collaborative scientific progress.
  • 02.Biological Sanity Checks: Every computational prediction must be rooted in biophysical plausibility and be testable in a wet-lab environment.
  • 03.Lifelong Learning: Embracing the rapid evolution of both AI tools and biological discoveries with an active, curious mind.

Interests Outside the Lab

Specialty Coffee Brewing

Applying molecular precision to water chemistry, grind profiles, and extraction parameters for the perfect V60 pour-over.

⌨️

Tech & Mechanical Keyboards

Assembling custom mechanical keyboards with tactile switches and compiling custom QMK firmware layouts.

📚

Non-fiction Reading

Deep-diving into complex topics like complex systems, history of science, evolution, and computer architectures.

🥾

Outdoor Hiking

Exploring lush tropical rainforests and mountain trails to unplug from monitors and recharge in nature.

Academic & Professional Resume

Roles, Credentials & Achievements

A

Asian University for Women

Instructor - Bioinformatics

2022-Present
B

BAF Shaheen College Chattogram

Lecturer - Biology

2021
D

DBME Research Group

Research Assistant

2018-2020
N

NIPS, Japan

Research Intern, Homeostatic Development Lab

2018